• SMi Source has 453 microlearning topics and 119 lessons when searching for Genetics

  • Lessons

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    Genetics: Introduction to Genetic Epidemiology

    Genetics: Introduction

    Multiple Sclerosis

    Lupus: Pathophysiology

    Genetics: Non-Mendelian

    Myelofibrosis

    Diabetes: Type 2- Pediatric Issues

    Oncology Primer: Mechanisms of Molecular Pathogenesis

    Immunology: Immune System Pathology

    Hepatology: Anatomy and Physiology of Liver and Overview of Liver Diseases

    Cardiovascular: Diabetes and Metabolic Syndrome

    Neurology: Parkinson's Disease

    Obesity

    Binge Eating Disorder: Biological Basis

    Post-traumatic Stress Disorder

    Anticoagulation: Thienopyridines

    Biology: DNA Discovery and Structure

    Multiple Sclerosis: History

    Lysosomal Storage Disorders: Sanfilippo Syndrome

    Dermatology: Atopic Dermatitis

    Hepatology: Anatomy and Physiology of Liver and Overview of Liver Diseases

    Psoriasis: Pathophysiology

    Alzheimer's Disease: Pathology

    Oncology: Head and Neck

    Rheumatoid Arthritis: Pathophysiology

    Oncology: Prostate Cancer

    Lysosomal Storage Disorders: Hunter Syndrome

    Cardiovascular: Platelet Biology

    Oncology: Sarcoma

    Alzheimer's Disease: Epidemiology of Dementia

    Lysosomal Storage Disorders

    Lysosomal Storage Disorders: Fabry Disease

    Cardiovascular: Acute Coronary Syndrome

    Alzheimer's Disease: Biomarkers

    Oncology: Melanoma

    Multiple Sclerosis: Gaining Knowledge on Immunology

    Hereditary Angioedema: Diagnosis

    Alzheimer's Disease: Diagnostic Criteria

    Biotech: Basics

    Lysosomal Storage Disorders: Gaucher Disease

    Lysosomal Storage Disorders: Metachromatic Leukodystrophy

    Biology: Translation - Protein Synthesis

    Oncology: Non-Small Cell Lung Cancer

    Binge Eating Disorder

    Diabetes: Type 1- Pathophysiology

    Biotech: Biologics

    Multiple Sclerosis: Diagnosis and Prognosis

    Oncology: Metastatic Breast Cancer

    Cardiovascular: Hyperlipidemia

    Drug R&D: Toxicology Applications

    Oncology Primer: Overview

    Oncology: Multiple Myeloma

    Oncology Primer: Invasion and Metastasis

    Neurology: Migraines

    HIV: Mutations and Resistance

    Atherosclerosis: Heart Failure

    HCV: Chronic Infection

    Cardiovascular: Atrial Fibrillation

    Schizophrenia

    HIV: Overview of Disease and Impact

    Infectious Disease: HBV and Chronic Infection

    Fetal Alcohol Spectrum Disorders: Assessing Risk

    Diabetes: Type 1

    Oncology Primer: Therapy Principles

    Obsessive Compulsive Disorder

    Osteoporosis: General

    Fetal Alcohol Spectrum Disorders: Screening

    Multiple Sclerosis: Oral Therapies

    Psoriasis: Clinical Picture

    Cardiovascular: Atrial Fibrillation Pathophysiology

    Biologics

    Major Depressive Disorder

    Myelodysplastic Syndrome

    HCV: Therapies and Prophylaxis

    Myelodysplastic Syndrome: Changes in Apoptosis

    Biology: Cell Cycle and Mitosis

    Multiple Sclerosis: Pathogenesis and Clinical Symptomology

    Biology: Systems Biology and Research Methodology

    Immunology: Autoimmune Disorders and Hypersensitivity

    Oncology Primer: Stem Cells

    Atherosclerosis: Pathophysiology

    Myelofibrosis: Treatment

    Atherosclerosis: Cholesterol Metabolism, Lipoproteins, and Residual Risk

    Rheumatoid Arthritis: Cytokines IL-beta; and IL-1Ra

    Multiple Sclerosis: Immunology

    Biotech: Biosimilars

    Opioids: Dependence and Addiction

    Cardiovascular: Heart Failure

    Diabetes: Type 2 - History

    Pharmacokinetics: For Non-PK Scientists

    Myelodysplastic Syndrome: Therapeutic Decisions

    Diabetes: Introduction to Clinical Trial Design

    Diabetes: Pathology of Complications

    Osteoporosis: Bone Biology and Remodeling

    Reproduction: Hypogonadism Pathophysiology

    Biology: Cell Structure and Mobility

    Diabetes: Type 2

    Cardiovascular: Hypertension

    Oncology: Colorectal Cancer

    Cardiovascular: Pulmonary Arterial Hypertension

    Cardiovascular: Myocardial Infarction

    Anxiety Disorders

    Diabetes: Type 2 Pathophysiology

    Pharmacokinetics: PK in Action

    Anticoagulation: Principles of Hemostasis and Bleeding Management

    Diabetes: Introduction to Incretin

    Cardiovascular: Cancer VTE

    Hereditary Angioedema

    Hereditary Angioedema: Pathophysiology

    Oncology Primer: Immunology of Cancer

    Atherosclerosis: Treatment

    Atherosclerosis: Lipid Lowering Agents

    Diabetes: Epidemiology

    Cardiovascular: Venous Thromboembolism

    HIV: Viral Load, CD4 Cells, and Mutations

    Immunology: Therapeutic Immunology

    Rheumatoid Arthritis: Clinical Presentation and Assessment

    Anticoagulation: Treatments I

    Lupus: Treatments

  • Microlearning Topics

  • Genetic Epidemiology

    Genetic Epidemiology

    Genetic Markers

    Genetic Markers: Single Nucleotide Polymorphisms (SNPs)

    Genetic Markers

    Genetic Markers

    Genetic Variation

    Genetic Variation

    Genetic Variation

    Genetic Mutations

    Genetic Epidemiology

    Analytic Study Designs

    Mendelian Genetics

    Modes of Inheritance and Pedigrees

    Mendelian Genetics

    Pedigrees

    Genetic Markers

    Genetic Advances and Technologies: DNA Sequencing and Dideoxynucleotide

    Genetic Markers

    Genetic Advances and Technologies: Human Genome Project

    Mendelian Genetics

    Mendelian Genetics and History of Cholesterol and Atherosclerosis

    Basics of DNA

    Building Proteins and Universal Genetic Code

    Genetic Markers

    Genetic Advances and Technologies: Advances Since the Human Genome Project

    Genetic Markers

    Genetic Advances and Technologies: Polymerase Chain Reaction and Primer

    Genetic Markers

    Genetic Advances and Technologies: Next Generation Sequencing (NGS)

    Genetic Epidemiology

    Analyzing Study Data: Confounding

    Mendelian Genetics

    History of Cholesterol and Atherosclerosis: 1950s to 1970s

    Mendelian Genetics

    History of Cholesterol and Atherosclerosis

    Mendelian Genetics

    Mendel's Law of Segregation

    Mendelian Genetics

    Mendel's Law of Independent Assortment

    Linkage Analysis

    Linkage

    Genetic Epidemiology

    Selected Analytic Study Designs

    Genetic Epidemiology

    Analyzing Study Data

    Mendelian Genetics

    Sex-Linked (X-Linked) Inheritance

    Cell Division

    Mitosis

    Cell Division

    Meiosis

    Emerging Hypotheses on Treatment

    Genetic Concepts: MS Genomics

    Lupus Risk Factors

    Genetics

    Linkage Analysis

    Complex Traits

    Triplet Repeat Disorders

    Triplet Repeat Expansions

    Basics of DNA

    The Units of Heredity

    Introduction

    Etiology: Genetic Factors

    Introduction

    Etiology: Genetic Factors

    Introduction

    Etiology: Genetic Factors

    Lupus Risk Factors

    Genetics
    Combination of Genetics and Environment

    Mosaicism

    Mosaicism

    Mosaicism

    Somatic Mosaicism

    Pathology

    Genetic Alterations: Gene Mutations

    Disease State

    Genetic Risk Factors

    Complex Inheritance

    Complex Inheritance, Variations on Dominance, Polygenic Traits, Pleiotropy, Penetrance and Expressiv...

    Genetic Instability

    Genetic Instability: Introduction

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Genetic Factors (Risk)
    The Etiology of Autoimmune Disease: ...

    Liver Diseases Overview

    Genetic Diseases, Hereditary Hemochromatosis

    Linkage Analysis

    Calculating Linkage

    Linkage Analysis

    Logarithm of the Odds (LOD) Score

    Triplet Repeat Disorders

    Fragile X Syndrome

    Genomic Imprinting

    Uniparental Disomy

    Basics of DNA

    Functions of Non-Coding DNA

    Basics of DNA

    Non-Coding DNA

    Basics of DNA

    Human Chromosomes and Karyotypes

    Triplet Repeat Disorders

    Huntington's Disease

    Basics of DNA

    Structure of DNA

    Genomic Imprinting

    Triplet Repeat Expansion

    Mitochondrial Mutations

    Mitochondrial Mutations

    Mosaicism

    X-Inactivation, Dosage Compensation, and Alport Syndrome (AS)

    Basics of DNA

    Human Genomic Landscape

    Epidemiology

    Risk Factors - Genetic Predisposition

    Etiology

    Genetics

    Overview of Obesity

    Genetics

    BED Pathophysiology

    Dopamine Dysregulation: Genetic Factors

    Pathology

    Genetic Alterations

    Etiology

    Genetic Factors

    Triplet Repeat Disorders

    Huntington's Disease: Huntingtin Gene (HTT)

    Genomic Imprinting

    Genomic Imprinting: Prader-Willi Syndrome (PWS) and Angelman Syndrome (AS)

    Clopidogrel

    Genetic Variation

    Summary: DNA Discovery and Structure

    DNA: The Genetic Material

    Lupus Risk Factors

    Combination of Genetics and Environment

    Etiology of Multiple Sclerosis

    Genetic Factors: Complex Interactions

    Genetics of Sanfilippo Syndrome

    Molecular Etiology

    Risk Factors

    Genetic Risk Factors in AD

    Etiology and Pathophysiology

    Genetic Predisposition

    Potential Factors in the Development of Psoriasis

    Genetic Factors

    Genetics

    APOE and Cholesterol Metabolism

    Anatomy and Pathophysiology

    Genetic Models of HNSCC Progression

    Risk Factors

    Genetics and Environmental Factors

    The Etiology of Prostate Cancer

    Role of Genetic Factors

    Etiology of Multiple Sclerosis

    Genetic Factors: MS Concordance
    Genetic Factors: Major Histocompatibility Complex II (MHCII)

    Genetics of Hunter Syndrome

    Molecular Etiology

    Hemostasis

    Disorders of Hemostasis: Abnormal Bleeding

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Genetic Factors (Risk)

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Genetic Factors (Introduction)

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease
    The Etiology of Autoimmune Disease: Genetic Factors (Risk)

    Soft Tissue Sarcomas (STSs)

    Anatomy and Pathophysiology: Genetic Considerations - Germline Mutations

    Non-modifiable Risk Factors

    Genetics: Familial DAD

    Non-modifiable Risk Factors

    Genetics: Sporadic DAD - Isoform ApoE4

    Etiology of Multiple Sclerosis

    Genetic Factors: MS Concordance
    Genetic Factors: Major Histocompatibility Complex II (MHCII)

    Lysosomal Storage Disorders: Overview and Definition

    Genetics

    Diagnosis of Fabry Disease

    Diagnostic Tests: Enzyme Assay and Molecular Genetic

    Coronary Atherosclerosis: Overview

    Genetic Predisposition

    Conclusions

    Conclusions: Head and Neck Cancer Epidemiology and Genetics

    Introduction

    Etiology: Genetic Factors

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Genetic Factors (Chromosomal Evidence: The Importance of HLA)

    Introduction

    Candidate Biomarkers in AD Based on Genetic Profile

    Anatomy and Pathophysiology

    Genetic Models of HNSCC Progression
    Metastasis and Early Tumor Progression

    Anatomy and Pathophysiology

    Melanoma Risk Factors: Numerous Nevi and Genetics

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Genetic Factors (Family and Population Studies)

    Additional concepts in MS Therapy

    Genetic Concepts

    Soft Tissue Sarcomas (STSs)

    Anatomy and Pathophysiology: Genetic Considerations - Frequent Chromosomal Translocations in Sarcoma...

    Classification Review and Diagnostic Considerations

    Diagnostic Considerations: Genetic Testing

    Criteria for the Diagnosis of Dementia Due to Alzheimer's Disease

    Familial Genetic Mutations

    Anatomy and Pathophysiology

    Mechanisms of Disease Development and Progression: Genetic Mutations and Impact

    Non-modifiable Risk Factors

    Genetics: Sporadic DAD - Newly Discovered Genes and Down Syndrome

    Introduction

    Disease Overview: Mortality
    MS Timeline
    Etiology
    Environmental Factors
    Infectiou...

    Emerging Hypotheses on Treatment

    Genetic Concepts: Interleukin Receptors

    Emerging Hypotheses on Treatment

    Genetic Concepts: Chances for Success

    Potential Factors in the Development of Psoriasis

    Potential Factors in Etiology of Psoriasis
    Genetic Factors
    Infectious Factors
    Drug an...

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease
    The Etiology of Autoimmune Disease: Genetic Factors (Risk)

    Emerging Hypotheses on Treatment

    Emerging Hypotheses on Treatment: Myelination-Targeted Antibodies
    Cell Therapy
    Human Stem ...

    Emerging Hypotheses on Treatment

    Genetic Concepts: Other Genes Potentially Involved in MS

    Anatomy and Pathophysiology

    Genetic Models of HNSCC Progression

    DNA Discovery

    Bacteriophage Experiment: DNA is the Genetic Material

    Etiology of Multiple Sclerosis

    Genetic Factors: MS Concordance

    Genetic Instability

    Chromosomal Instability

    What is Biotechnology?

    Genetic Engineering: The Foundation of Biotech

    Genetics

    High Serum Cholesterol Levels and AD

    Genetics of Hunter Syndrome

    Inheritance Pattern

    Genetics of Gaucher Disease

    Molecular Etiology

    Genetics of Gaucher Disease

    Inheritance Pattern

    Genetics of Sanfilippo Syndrome

    Inheritance Pattern

    Genetics of Metachromatic Leukodystrophy

    Molecular Etiology

    Genetics of Metachromatic Leukodystrophy

    Inheritance Pattern

    Genetics of Fabry Disease

    Molecular Etiology

    Genetics of Fabry Disease

    Inheritance Pattern

    Etiology of Multiple Sclerosis

    Genetic Factors: Major Histocompatibility Complex II (MHCII)

    What is Biotechnology?

    The History of Biotechnology
    What is Biotechnology?
    A Global Industry
    The Evolution o...

    Overview of Obesity

    Overweight/Obese Defined
    Body Mass Index
    Waist Circumference and Obesity
    Cause of Obe...

    Additional concepts in MS Therapy

    Immunologic Concepts
    Genetic Concepts
    Neurodegeneration
    Neuroprotection
    Remyelin...

    Introduction

    Introduction

    Introduction

    Introduction

    Liver Diseases Overview

    Liver Disease Overview: Key Concepts

    Introduction

    Introduction

    Overview: Translation (Protein Synthesis)

    Translation: Protein Synthesis (Overview)

    Disease Overview

    Etiology

    Disease State

    Classification: NSCLC Classification Based on Genomics

    Introduction

    Etiology

    Epidemiology

    Etiology

    Summary: Psoriasis

    Potential Factors in Etiology of Psoriasis

    Potential Factors in the Development of Psoriasis

    Potential Factors in Etiology of Psoriasis

    Diagnosis of Gaucher Disease

    Clinical Signs and Symptoms

    BED Disease State

    Disease Onset and Clinical Course

    Pathology of T1DM

    Type 1 Diabetes: Risk Factors

    Introduction

    Protein Structure and Function

    Differential Diagnosis

    Differential Diagnosis: Other Diseases that Share Some MS Features

    Diagnosis and Treatment

    Diagnostic Components/Diagnostic Confirmation

    Overview of Breast Cancer

    Risk Factors for Breast Cancer

    Summary: Psoriasis

    Psoriasis Definition
    Potential Factors in Etiology of Psoriasis
    Pathophysiology of Psorias...

    Disease State

    Etiology of Hyperlipidemia

    How Do We Identify DNA Toxicants?

    In Vivo Tests

    The Hallmarks of Cancer

    Enabling Characteristics

    Molecular and Cellular Basis

    Abnormal Plasma-like Myeloma Cells

    Risk Factors

    Risk Factors: Overview

    Invasion and Metastasis: Introduction

    Overview of Cancer: Hallmark Capabilities of Cancer

    Physiology of Immune System Dysregulation

    Pathophysiology of Psoriasis

    Triggers and Risk Factors for Migraine

    Risk Factors

    Viruses and Mutation

    Mutations

    Diagnosis of MLD

    Diagnostic Components and Findings

    Atherosclerosis: Risk Factors

    Risk Factors

    Atherosclerosis: Risk Factors

    Risk Factors

    HCV Life Cycle

    Viruses Require Cells as Hosts

    Natural History of Type 1 Diabetes

    Natural History of Type 1 Diabetes

    How Do We Identify DNA Toxicants?

    In Vitro Tests
    In Vivo Tests

    Causes of Atrial Fibrillation

    Atrial Fibrillation Without Associated Heart Disease - Lone AF

    Etiology

    Pathogenesis of Schizophrenia

    Pathophysiology

    Overview: Pathogenesis

    Resistance Testing

    Genotypic Antiretroviral Resistance Testing

    Overview of Obesity

    Contributing Factors to Overweight/Obesity

    Coronary Atherosclerosis: Overview

    Risk Factors and Atherosclerosis

    Pathophysiology

    Overview

    Recombination

    Two Copies of RNA

    HBV Life Cycle

    Viruses Require Cells as Hosts

    Etiology of Multiple Sclerosis

    Cause of Multiple Sclerosis

    Summary: Fetal Alcohol Spectrum Disorders (FASD) Prevention

    Risk Factors

    Potential Factors in the Development of Psoriasis

    Geographical Location

    Anatomy and Pathophysiology

    Mechanisms of Disease Development and Progression: Immune System Evasion

    Classification Review and Diagnostic Considerations

    Diagnostic Considerations

    Pathology of T1DM

    Type 1 Diabetes: Risk Factors

    Targeted Therapies

    Therapies that Target Oncogenic Fusion Proteins

    Viruses and Mutation

    Viruses Require Cells As Hosts
    Mutations
    Mutations Caused by Reverse Transcriptase

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Environmental Factors

    Summary: Psoriasis

    Psoriasis Definition

    Lysosomal Storage Disorders

    Epidemiology

    Etiology

    Heritability

    HBV Life Cycle

    Viruses Require Cells as Hosts
    Knowledge Check: HBV and Chronic Infection

    HBV Life Cycle

    Viruses Require Cells as Hosts

    Pathogenesis of Primary Osteoporosis

    Osteoporosis in Men

    Risk Factors

    AD and Environmental Risk Factors

    HBV Life Cycle

    Viruses Require Cells as Hosts

    Tumor Suppressor Genes

    Tumor Suppressor Genes: Introduction

    Atherothrombosis

    Overview: Atherosclerotic Process

    Summary

    HIV Life Cycle

    Clinical Course of Alzheimer's Disease

    AD Progression, Biomarkers and Pharmacological Therapy

    Etiology of Multiple Sclerosis

    Cause of Multiple Sclerosis
    Environmental Factors

    Fetal Alcohol Spectrum

    Damage Due to Alcohol Exposure

    Mechanisms of Molecular Pathogenesis: Summary

    Mechanisms of Molecular Pathogenesis: Summary

    Biomarkers

    Examples of Current Biomarkers

    Introduction to PK

    Pharmacokinetics: Patient Characteristics

    Lysosomal Storage Disorders: Overview and Definition

    Lysosomal Storage Disorders: Overview and Definition

    TIDM and Autoimmune Disorders

    Immunotherapy of Type 1 Diabetes

    Drug Discovery

    Biomarkers

    Introduction: Psoriasis

    Introduction: Psoriasis

    Anatomy and Pathophysiology

    Melanoma Risk Factors: UV Exposure and Compromised Immune System

    Introduction

    Introduction: Soft Tissue and Bone Sarcomas

    Soft Tissue Sarcomas (STSs)

    Anatomy and Pathophysiology: Mechanisms of Disease Development and Progression

    Risk Factors for AD

    Risk Factors for AD

    Causes of Atrial Fibrillation

    Causes of Atrial Fibrillation: Overview

    Causes of Atrial Fibrillation (AF), Associated Conditions

    Causes of Atrial Fibrillation (AF): Overview

    Epidemiology and Natural History

    Epidemiology

    Pathology of T1DM

    Natural History of Type 1 Diabetes

    Biological Products/Cell Therapy

    Discovery and Development of Biologics: Cell Therapy

    Heart Failure: Causes

    Index Event
    Nature of Index Event
    Compensatory Mechanisms
    Left Ventricular Remodeling

    Summary: Pathophysiology of Lupus

    Summary: Pathophysiology of Lupus

    Etiology

    Influencing Factors

    Epidemiology and Incidence

    Predisposing Causes of Myelodysplastic Syndromes Primary MDS (de novo MDS)

    Summary: Epidemiological Research

    Summary: Epidemiological Research

    Hunter Syndrome: Introduction

    Hunter Syndrome: Introduction

    Fabry Disease: Introduction

    Fabry Disease: Introduction

    Atherosclerosis: Overview and Statistics

    Overview

    Heart Failure: Causes

    Compensatory Mechanisms

    Introduction

    Define a Biologic (Clarification of Terminology, FDA Changes)

    HCV Vaccines

    Challenges in Vaccine Development

    Introduction

    Myeloma Etiology

    Classification and Staging

    Prognosis

    Introduction to Immunopathology

    Autoimmune Diseases: General Mechanism Underlying Autoimmune Disease

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease

    Chromosome Abnormalities in MDS

    Chromosome Abnormalities: Aneuploidy

    Chromosome Abnormalities in MDS

    Clonality and Karyotypic Evolution

    Chromosome Abnormalities in MDS

    Molecular Models for Chromosome Abnormalities

    DNA Discovery

    Bacteriophage Experiment

    Overview: The Cell Cycle and Mitosis

    The Cell Cycle and Mitosis: Overview

    Animal Models of MS

    TMEV Infection Model

    Biomarkers

    Examples of Current Biomarkers
    Candidate Biomarkers

    Model Development and Implementation

    Model-Centric Data Integration, Development, and Collection

    Autoimmune Diseases: Introduction

    General Mechanism Underlying Autoimmune Disease

    What is Biotechnology?

    The Evolution of Biotechnology

    Biopharmaceuticals

    Making Biopharmaceuticals Better

    Mechanisms of Select Autoimmune Disorders

    Rheumatoid Arthritis: TH17

    Introduction: Psoriasis

    Definition of Psoriasis

    Overview of Obesity

    Cause of Obesity

    Soft Tissue Sarcomas (STSs)

    Anatomy and Pathophysiology: Familial Predisposition

    Conclusions and Future Directions

    Sarcomas: Conclusions and Future Directions

    Clopidogrel

    Drug Interactions and Hyporesponse

    Hunter Syndrome: Introduction & Overview

    Etiology: Mucopolysaccharidoses (MPS)

    Stochastic or Clonal Evolution Model

    Stochastic or Clonal Evolution Model

    Epidemiology

    Juvenile-Onset Parkinson's Disease

    Atherosclerosis Contribution to Cardiovascular Diseases

    Coronary Artery Disease: Heart Failure

    Schizophrenia Disease

    Schizophrenia

    Risk Stratification Systems

    Mutations Linked to PMF and Other Myeloproliferative Neoplasms

    Disease Overview

    Definition of Multiple Sclerosis
    Prognosis
    Clinical Presentation
    Patient Descriptions...

    Risk Factors for Atherosclerosis

    Risk Factors and Atherosclerosis

    Dyslipidemia Disease State

    Etiology

    Autoimmune Diseases: Introduction

    General Mechanism Underlying Autoimmune Disease
    The Breakdown of Tolerance
    The Breakdown o...

    Introduction

    Protein Structure and Function

    HCV Life Cycle

    Viruses Require Cells as Hosts
    HCV Infection
    HCV Translation
    HCV Replication
    Tes...

    What is HCV?

    HCV Genotypes

    Pathophysiology

    Immunopathophysiology: Epstein-Barr Virus (EBV)

    Gene Silencing: DNA Methylation

    Genes Affected by Methylation in MDS: Tumor Suppressor Genes

    Cytogenetic Subgroups in MDS

    Cytogenetic Subgroups in MDS

    IL-1Ra

    IL-1Ra Inhibits IL-1β

    Epidemiology

    Demographics

    Mechanisms of Select Autoimmune Disorders

    Systemic Lupus Erythematosus: Multisymptom Disease

    Physiology of Immune System Dysregulation

    Overview of Immune Dysregulation

    Summary: Psoriasis

    Pathophysiology of Psoriasis

    Soft Tissue Sarcomas (STSs)

    Anatomy and Pathophysiology: Li-Fraumeni syndrome

    Pathophysiology of Atrial Fibrillation

    Atrial Fibrosis

    Mechanisms of Select Autoimmune Disorders

    Rheumatoid Arthritis: Early Stages of RA

    Causes of Atrial Fibrillation (AF), Associated Conditions

    Familial Atrial Fibrillation
    Obesity and Atrial Fibrillation

    Biological Products

    Manufacturing Process

    Sanfilippo Syndrome: Introduction

    Sanfilippo Syndrome: Introduction and Overview

    Metachromatic Leukodystrophy: Introduction

    Metachromatic Leukodystrophy: Introduction and Overview

    Immunotherapies

    Tumor Cell Therapies

    Introduction

    Multiple Myeloma (MM)
    Interactive Exercise: Cancer Vocabulary
    Spectrum of Diseases
    Pr...

    Prenatal and Postnatal Diagnosis

    Diagnosis of HAE In Pregnancy

    Neurobiology of Addiction and Withdrawal

    Addiction, Tolerance, and Withdrawal

    Pathophysiology

    Immunopathophysiology: Myelin-Reactive T Cells
    Immunopathophysiology: T Cell Initiation of MS -...

    Introduction

    Define a Biologic (Clarification of Terminology, FDA Changes)
    Protein Structure and Function

    Molecular and Cellular Basis

    Abnormal Plasma-like Myeloma Cells
    Normal B Cell Development
    Myeloma Cell Development

    Overview of Heart Failure

    Classification of Heart Failure: Conventional Classification

    Diagnostic Workup

    Laboratory Tests for AE (Without Urticaria)

    Atherosclerosis: Overview and Statistics

    Overview

    HIV Retrovirus

    HIV Core

    Viruses and Mutation

    Viruses Require Cells As Hosts

    Type 2 Diabetes Mellitus (T2DM)

    Natural History of T2DM: Summary

    Type 2 Diabetes Mellitus (T2DM)

    Natural History of T2DM: Summary

    What are the Determinants of PK? ADME

    ADME

    What is HBV?

    HBV Genome

    Mutations in Genes Responsible for Cell Proliferation

    Changes in Apoptosis and Proliferation

    Gene Silencing: DNA Methylation

    Genes Affected by Methylation in MDS: Tumor Suppressor Genes

    Hypomethylating Agents

    Gene Silencing Following DNA Methylation

    Risk Factors

    Alcoholism

    Risk Factors

    Alcohol Dependence (Alcoholism)

    Introduction to Diabetes and Diabetes Terminology

    Introduction to Diabetes and Diabetes Terminology

    Summary: Diabetes: Type 1 Pathophysiology

    Pathophysiology of Type 1 Diabetes

    Microvascular Complications

    Diabetic Nephropathy: Risk Factors, Treatment

    Introduction: Psoriasis

    Definition of Psoriasis
    Psoriasis Skin Dysregulation

    Psoriatic Arthritis

    Psoriatic Arthritis (PsA) Pathophysiology

    Overview of Obesity

    Risk Factors Associated with Being Obese or Overweight

    Peak Bone Mass

    Factors Affecting Peak Bone Mass

    Anatomy and Pathophysiology

    Risk Factors: Diet, Oral Hygiene and Inherited Conditions

    Introduction

    Introduction

    Pathophysiology of Male Hypogonadism

    Tertiary Male Hypogonadism: Kallman Syndrome, GnRH Deficiency, GPR54, Opioid Use

    Pathophysiology of Atrial Fibrillation (AF)

    Atrial Fibrosis

    Gaucher Disease: Introduction

    Gaucher Disease: Introduction

    Hereditary Angioedema: Summary

    Hereditary Angioedema: Summary

    Prevalence and Incidence of CVD

    Prevalence and Incidence of Cardiovascular Disease (CVD): Overview

    Basaglar T1DM: Summary

    Pathophysiology of Type 1 Diabetes

    Pathophysiology

    Overview
    T Cell Initiation of MS Blood Brain Barrier
    B Cells and Autoantibodies in Diseas...

    Type 2 Diabetes Mellitus (T2DM)

    Natural History of T2DM: Summary

    Autoimmune Disease Processes

    The Etiology of Autoimmune Disease: Environmental Factors (Infectious Agents)
    The Etiology of A...

    Cellular Organelles

    Cellular Organelles

    Overview of Osteoporosis

    Bone Biology and Bone Loss

    Disease State

    Risk Factors

    Diagnostic Workup

    Causative and Facilitative Factors

    T2DM Diagnosis

    Signs and Symptoms

    Etiology of Hypertension

    Risk Factors

    Introduction

    The Critical Path for Medical Product Development
    The Immune System Modulators
    Interactive...

    Recombination

    HIV Subtypes
    Two Copies of RNA
    Recombination

    Resistance Testing

    Anti-Retroviral Resistance Testing
    Genotypic Antiretroviral Resistance Testing
    Phenotypic ...

    Heart Failure: Causes

    Compensatory Mechanisms

    Oral Dosing

    Bioavailability (F)

    Chromosome Abnormalities in MDS

    Chromosome Abnormalities: Translocations and Inversions
    Interactive Activity: Chromosomes Abnor...

    Hypomethylating Agents

    Gene Silencing Following DNA Methylation

    Autoimmune Diseases: Introduction

    Autoimmune Diseases: Introduction

    Introduction to PK

    Drug Concentration at Target Site
    Different Types of Drug Molecules
    Pharmacokinetics vs. P...

    Overview of Colorectal Cancer

    Non-Modifiable Risk Factors

    Autoimmune Diseases: Introduction

    Autoimmune Diseases: Introduction
    Epidemiology and Impact

    Liver Diseases Overview

    Hepatitis Due to Drugs, Toxins, and Alcohol: Alcoholic Liver Disease

    Liver Diseases Overview

    Primary Sclerosing Cholangitis (PSC)

    Primary Biliary Cirrhosis: Key Concepts

    Primary Biliary Cirrhosis: Key Concepts

    Non-Small Cell Lung Cancer: Introduction

    Non-Small Cell Lung Cancer: Introduction

    Pathophysiology

    Nephropathy

    Diagnosis and Prognosis

    Confirmation with Complete Right Heart Catheterization

    Diagnosis and Treatment

    Diagnostic Components

    Diagnosis of Hunter Syndrome

    Diagnostic Tests

    Epidemiology

    Incidence, Prevalence, and Demographics

    Diagnosis of Gaucher Disease

    Diagnostic Tests and Surveillance

    Atopic Dermatitis: Introduction

    Atopic Dermatitis: Introduction

    Epidemiology

    Risk Factors

    Prostate Cancer: Introduction

    Prostate Cancer: Introduction

    Anxiety Disorders Disease: Introduction

    Prevalence of Anxiety Disorders

    Migraine

    The Evolution of Migraine

    Chromosome Abnormalities in MDS

    Chromosomes
    Chromosomes: Number and Structure
    Interactive Activity: Chromosomes - Number a...

    Epidemiology and Incidence

    Increasing Incidence with Increasing Age of Myelodysplastic Syndromes
    Gender and Myelodysplasti...

    Atherosclerosis: Overview and Statistics

    Overview
    Statistics

    Summary

    HIV Entry
    HIV Life Cycle
    Splicing
    Virus Maturation
    Subtypes
    Recombination

    Introduction to Immunopathology

    Autoimmune Diseases: Epidemiology and Impact
    Autoimmune Diseases: General Mechanism Underlying ...

    Mutations in Genes Responsible for Cell Proliferation

    Changes in Apoptosis and Proliferation
    Oncogenes
    Oncogenes: Small G Proteins (Ras)
    On...

    Gene Silencing: DNA Methylation

    Epigenetic Changes: DNA Methylation
    CpG Islands and Histones Deacetylases
    Genes Affected b...

    Hypomethylating Agents

    Mechanism of DNA Methylation
    Gene Silencing Following DNA Methylation
    Hypomethylating Agen...

    Summary: Cell Structure and Mobility

    Cell Structure and Mobility: Summary

    Summary: Fetal Alcohol Syndrome

    Summary: Fetal Alcohol Syndrome

    Fetal Alcohol Spectrum

    Fetal Alcohol Syndrome (FAS) Alcohol Effects
    Fetal Alcohol Spectrum Disorders (FASD)
    Fetal...

    Summary: Fetal Alcohol Spectrum Disorders (FASD) Prevention

    Preventing Fetal Alcohol Spectrum Disorders (FASD)
    Routine Alcohol Screening
    Risk Factors

    Type 2 Diabetes Mellitus

    Common Risk Factors for Type 2 Diabetes

    Biopharmaceuticals

    Biopharmaceuticals
    Patents and Generics
    Biopharmaceuticals: Specificity of Action
    Mak...

    Psoriatic Arthritis

    Pathophysiology of Psoriatic Arthritis (PsA)
    Psoriatic Arthritis (PsA) Pathophysiology

    Non-Bioequivalent Insulins

    Humulin R U-500: Real World Usage and Outcomes

    Biological and Physicochemical Determinants of PK

    Drug Elimination: Metabolism and Excretion

    Patient Types and Risk Factors for Bleeding

    Bleeding Disorders

    GLP-1 Receptor Agonists for T2DM

    GLP-1 Receptor Agonists: Increasing Duration of Action

    Definition and Classification

    Spectrum of Disorders

    Overview: Cancer VTE

    Venous Thromboembolism (VTE) Overview

    Country-Specific Definitions and Regulatory Guidelines

    India Ministry of Science and Technology (MST)

    Overview of Classification of Angioedema (AE)

    Allergic Angioedema (Association with Urticaria)

    Symptoms and Clinical Course of HAE

    Overview: HAE Due to Decreased C1-INH

    Classification Review and Diagnostic Considerations

    Angioedema Overview

    Epidemiology

    Risk Factors

    Risk Factors for CHD and MI

    Risk Factors

    Concepts in Cancer Immunology

    Cancer Immunosurveillance

    Additional Recommendations and Position Statements

    National Lipid Association (NLA) Recommendations for Patient-Centered Management of Dyslipidemia

    Special Populations

    NLA: South Asians

    Mechanisms of Select Autoimmune Disorders

    Systemic Lupus Erythematosus

    What is HCV?

    HCV Genome: Regions Encoding Structural and Non-Structural Genes
    Hepatitis Viruses
    Phyloge...

    HIV Retrovirus

    Reverse Transcriptase
    HIV Core
    HIV Messenger RNA
    HIV Integrase

    HCV Vaccines

    The Immune Response
    Are Vaccines Feasible with Hepatitis Viruses?
    Routes to an Effective H...

    What are the Determinants of PK? ADME

    Interactive Exercise: Drug Absorption and Elimination
    Elimination: Metabolism & Excretion
    ...

    Oral Dosing

    Absorption
    Lag Time
    Bioavailability (F)
    Interactive Exercise: Changing Dose
    Bioe...

    Osteoporosis and Obesity

    Background

    Epidemiology and Risk Factors for PAH

    Risk Factors

    Statins

    Side Effects

    PCSK9 Inhibitors

    Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

    Atherothrombosis

    Overview: Atherothrombosis
    Interactivity: Unstable Plaque
    Interactivity: Thrombus Formatio...

    Classification and Staging

    Classification of Myeloma
    Diagnostic Criteria
    Interactive Exercise: Myeloma Classification...

    Chromosome Abnormalities in MDS

    Chromosomes
    Chromosomes: Number and Structure
    Interactive Activity: Chromosomes - Number a...

    Risk Factors

    Who's at Risk for Having Children with FASD?
    Risk Factors Based on Study Population
    In...

    Risk Factors

    Alcohol Dependence (Alcoholism)
    Interactive Exercise: Who's at Risk?
    Risk Factors Base...

    Drug Discovery

    Drug Discovery
    Target vs. Platform-driven Discovery
    Target Validation
    Targeting Strat...

    PK in Action

    PK Prediction

    Non-Bioequivalent Insulins

    Humulin R U-500: Evaluating Dose Regimens, Clinical Pharmacology, Costs, and Adherence

    Cancer Immunotherapy

    Adoptive T Cell Transfer

    What is HBV?

    Hepatitis Viruses
    HBV (Molecular Biology of HBV)
    The Structure of HBV
    HBV Genome

    Clinical Features of Angioedema Without Urticaria (Bradykinin-Mediated)

    HAE Due to Decreased C1-INH

    Epidemiology

    Overview of HAE Epidemiology

    Relationship between Obesity, Diabetes and Cardiovascular Disease

    Obesity: Pathophysiology of Fat Cells

    Biological Products/Biologics vs. Biosimilars

    How Similar Is Similar

    Biological Products/Gene Therapy

    Discovery and Development of Biologics: Gene Therapy

    Introduction to Immunopathology

    Organ Transplant Rejection: Class I MHC and Class II MHC Proteins
    Organ Transplant Rejection: H...

    VTE Clinical Picture: Risk Factors and Comorbid States

    Comorbid States

    Biological Products/Biologics vs. Biosimilars

    Demonstrating Biosimilarity

    Lysosomal Storage Disorders: Introduction

    Lysosomal Storage Disorders: Introduction

    Pathophysiology

    Pathogenesis

    Heart Failure: Causes

    Nature of Index Event

    Marketplace

    Multiple Sclerosis

    Summary: Myelodysplastic Syndromes

    Apoptosis Followed by Proliferation

    Liver Diseases Overview

    Hepatitis Due to Drugs, Toxins, and Alcohol

    Biological Products/Recombinant Proteins

    Discovery and Development of Biologics: Recombinant Biologics

    Viral Genotype and Resistance

    Genotype and Phenotype

    Introduction

    Multiple Myeloma (MM)

    Summary: Myelodysplastic Syndromes

    Defining Myelodysplastic Syndromes
    Apoptosis Followed by Proliferation
    Summary: Myelodyspl...

    Mutations

    Why Mutations Occur

    Lysosomal Storage Disorders

    Classification: Oligosaccharidoses, Cystinosis, and Niemann-Pick Type C Disease

    Autoimmune Disorders

    Mechanisms: The Breakdown of Tolerance Molecular Mimicry

    Autoimmune Diseases: Introduction

    The Breakdown of Tolerance: Molecular Mimicry

    Relationship between Obesity, Diabetes and Cardiovascular Disease

    Obesity, Diabetes and Cardiovascular Disease
    Obesity: Pathophysiology of Fat Cells
    Obesity...

    VTE Clinical Picture: Risk Factors and Comorbid States

    Risk Factors and Comorbid States

    Forms of Lupus

    Neonatal Lupus

    Pharmacokinetics: Absorption

    Low Bioavailability

    Clinical Manifestations

    Signs and Symptoms

    Metachromatic Leukodystrophy: Introduction and Overview

    Etiology

    Epidemiology

    Longitudinal Studies: Age-Associated Diseases

    Autoimmune Disorders

    Mechanisms: The Breakdown of Tolerance Molecular Mimicry
    Mechanisms: Loss of T Cell Anergy

    Mechanisms of Autoimmune Disease: The Breakdown of Tolerance

    The Breakdown of Tolerance: Molecular Mimicry

    Autoimmune Diseases: Introduction

    The Breakdown of Tolerance
    The Breakdown of Tolerance: Molecular Mimicry
    Mechanisms: Loss ...

    Pathophysiology

    T Cell Initiation of MS

    Heart Failure: Risk Factors

    Risk Factors

    Heart Failure: Risk Factors

    Risk Factors

    HCV Life Cycle

    HCV Replication

    Pathophysiology

    Anatomical Pathophysiology: Histological Patterns

    Histological/Biological Changes

    Proteinaceous Deposits

    Autoimmune Disease Processes

    Consequences of Autoimmune Diseases: Common Autoimmune Diseases

    Pathophysiology

    Immunopathophysiology: T Cell Initiation of MS

    Viral Genotype and Resistance

    Genotype and Phenotype
    Gene Expression in HIV
    Mutation and Resistance
    Resistance to D...

    Marketplace

    Stroke
    Diabetes Mellitus
    Growth Defects
    Anemia
    Neutropenia
    Hepatitis
    R...

    Autoimmune Disease Processes

    Consequences of Autoimmune Diseases: TNF-α In Autoimmune Disease: Potential Harm OR Benefit?

    Introduction to Therapeutic Immunology

    Categories of Biologic Therapy

    Criteria for the Diagnosis of Dementia Due to Alzheimer's Disease

    NINCDS-ADRDA Update

    Mechanisms of Autoimmune Disease: The Breakdown of Tolerance

    Mechanisms of Autoimmune Disease: The Breakdown of Tolerance
    The Breakdown of Tolerance: Molecu...

    Mechanisms of Autoimmune Disease: The Breakdown of Tolerance

    Mechanisms of Autoimmune Disease: The Breakdown of Tolerance
    The Breakdown of Tolerance: Molecu...

    Autoimmune Disease Processes

    Consequences of Autoimmune Diseases: Progression and Destruction in Autoimmune Disorders (Mechanisms...

    Advancing Technologies

    Biomarkers: Inflammation Biomarkers

    Marketplace

    Stroke
    Diabetes Mellitus
    Growth Defects
    Anemia
    Neutropenia
    Hepatitis
    R...

    Introduction to Therapeutic Immunology

    Edward Jenner: Vaccination
    Vaccination Successes
    Therapeutic Immunology: Immunodiagnostics...

    Mutations

    Why Mutations Occur
    Loss of Drug Effectiveness
    Mutations Selection by Drugs
    Cross Res...

    Disease Definition and Clinical Course

    Course of Disease

    Typical Course of Plaque Psoriasis

    Onset, Episodes, Flare-Ups, Triggers
    Complications and Comorbidities of Psoriasis

    Typical Course of Plaque Psoriasis

    Complications and Comorbidities of Psoriasis

    Introduction to Monoclonal Antibodies

    Four General Classes of mAb Therapies

    Standard Agents: Therapeutic Challenges

    Therapeutic Challenges of Antithrombotic Treatment

    Introduction to Monoclonal Antibodies

    Antibodies as Therapy
    Early Antibody Therapy: Polyclonal Antibodies
    Hybridoma Technology: ...

    Clinical Applications of Monoclonal Antibodies

    A Closer Look At mABS Used as Therapies

    Steroids

    Glucocorticoids: Mode of Action
    The Anti-Inflammatory Effects of Corticosteroids
    Glucocort...

    Steroids

    Glucocorticoids: Side Effects

    Advancing Technologies

    Biomarkers: Disease Process-Specific Biomarkers
    Biomarkers: Inflammation Biomarkers
    Biomar...

    Clinical Applications of Monoclonal Antibodies

    Clinical Applications of Monoclonal Antibodies: Learning Objectives
    Detection, Diagnosis, and M...

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